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Patent

NMDA Antagonists - New selective compounds to the NR2B subunit with high affinity

he NMDA receptor, an ion channel consisting of several protein subunits, is involved in the pathophysiology of chronic neurodegenerative diseases, depression, pain and alcoholism. Different subtypes of NMDA receptors can be categorized based on their subunit composition. The NR2B subunit expression is mostly localized in forebrain regions including cortex, hippocampus and striatum.

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PROvendis GmbH
Dipl.-Ing. Alfred Schillert
Phone: +49 (0)208/94105 10
Email: kontakt@provendis.info
Autor: Constanze Hasenbein, Dipl.-Biol., Tel.: +49 (0)208/94105-41

Further information: PDF
Topic: Biotechnology, New Materials and Chemistry, Health and Medicine
Source: TechnologieAllianz e. V.